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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKI67 All Species: 7.58
Human Site: T1139 Identified Species: 23.81
UniProt: P46013 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46013 NP_001139438.1 3256 358694 T1139 P P P E S V D T P T S T K Q W
Chimpanzee Pan troglodytes XP_508147 3257 358658 T1139 P P P E S V D T P T S T K Q W
Rhesus Macaque Macaca mulatta XP_001089669 2126 233775 D169 V K E D T A D D S K D S V A Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_001074586 3177 350846 A1124 T Q P V R T P A S T K R L S K
Rat Rattus norvegicus XP_225460 3119 343332 T1124 P H T E S V R T P A S T K R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421822 2556 283606 R599 P H R L S S K R S S G S A T V
Frog Xenopus laevis NP_001128553 2510 270869 A553 S P A K M T L A K R S P A K M
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782273 1825 188999
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 55.1 N.A. N.A. 43.1 43.1 N.A. N.A. 22.4 21.7 N.A. N.A. N.A. N.A. N.A. 24.1
Protein Similarity: 100 98.7 57.3 N.A. N.A. 58.2 57 N.A. N.A. 38.5 38.1 N.A. N.A. N.A. N.A. N.A. 34.9
P-Site Identity: 100 100 6.6 N.A. N.A. 13.3 60 N.A. N.A. 13.3 13.3 N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 26.6 N.A. N.A. 13.3 66.6 N.A. N.A. 26.6 26.6 N.A. N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 13 0 25 0 13 0 0 25 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 13 0 0 38 13 0 0 13 0 0 0 0 % D
% Glu: 0 0 13 38 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % G
% His: 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 13 0 13 0 0 13 0 13 13 13 0 38 13 13 % K
% Leu: 0 0 0 13 0 0 13 0 0 0 0 0 13 0 13 % L
% Met: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 13 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 38 38 0 0 0 13 0 38 0 0 13 0 0 0 % P
% Gln: 0 13 0 0 0 0 0 0 0 0 0 0 0 25 13 % Q
% Arg: 0 0 13 0 13 0 13 13 0 13 0 13 0 13 0 % R
% Ser: 13 0 0 0 50 13 0 0 38 13 50 25 0 13 0 % S
% Thr: 13 0 13 0 13 25 0 38 0 38 0 38 0 13 0 % T
% Val: 13 0 0 13 0 38 0 0 0 0 0 0 13 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _